Dr Thomas Brenn

Widespread spontaneous hyperproliferation, melanosis and melanoma in Hgf-Cdk4R24C mice van der Weyden, L., Arends, M., Brenn, T., Tüting, T. & Adams, D. 1 Feb 2018 Melanoma research. 28, 1

Melanocytic naevi with perineurial differentiation a distinctive variant of neurotised naevi and a diagnostic pitfall with desmoplastic melanoma Ferreira, I., Kind, P., Van Den Berghe, I., Melly, L., Offner, F., Hornick, J. L. & Brenn, T. 14 Dec 2017 Histopathology.

A structurally distinct immunosuppressive TGF-β mimic from an intestinal helminth that potently induces murine and human regulatory T cells Johnston, C. J. C. , Smyth, D. , Kodali, R. B. , White, M. P. J. , Harcus, Y. , Filbey, K. , Hewitson, J. , Hinck, C. S. , Ivens, A. , Kemter, A. , Kildemoes, A. O. , Le Bihan, T. , Soares, D. , Anderton, S. , Brenn, T. , Wigmore, S. , Woodcock, H. , Chambers, R. C. , Hinck, A. P. , McSorley, H. & Maizels, R. 23 Nov 2017 Nature Communications. 8, 13 p., 1741

Atypical fibroxanthoma and pleomorphic dermal sarcoma harbor frequent NOTCH1/2 and FAT1 mutations and similar DNA copy number alteration profiles Griewank, K. G., Wiesner, T., Murali, R., Pischler, C., Müller, H., Koelsche, C., Möller, I., Franklin, C., Cosgarea, I., Sucker, A., Schadendorf, D., Schaller, J., Horn, S., Brenn, T. & Mentzel, T. 3 Nov 2017 Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Cutaneous Sweat Gland Carcinomas with Basaloid Differentiation: An Update with Emphasis on Differential Diagnoses Flux, K. & Brenn, T. Sep 2017 Clinics in laboratory medicine. 37, 3, p. 587-601 15 p.

Malignant mesenchymal neoplasms of the dermis and subcutis mimicking benign lesions: a case-based review Mentzel, T. & Brenn, T. 12 Jul 2017 Virchows Archiv.

Diagnostic Challenges in Dermatopathology Brenn, T. 1 Jun 2017 Surgical pathology clinics. 10, 2, p. xi-xii

Atypical Fibroxanthoma Revisited Mentzel, T., Requena, L. & Brenn, T. Jun 2017 Surgical pathology clinics. 10, 2, p. 319-335 17 p.

Update on Malignant Sweat Gland Tumors van der Horst, M. P. J. & Brenn, T. Jun 2017 Surgical pathology clinics. 10, 2, p. 383-397 15 p.

S-100 protein expression of spindle cells in spindle cell lipoma: a diagnostic pitfall Mentzel, T., Rutten, A., Hantschke, M., Hornick, J. L. & Brenn, T. 21 Jul 2016 Virchows Archiv.

Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole body energy expenditure Liakath-Ali, K., Vancollie, V. E., Lelliott, C. J., Speak, A. O., Lafont, D., Protheroe, H. J., Ingvorsen, C., Galli, A., Green, A., Gleeson, D., Ryder, E., Glover, L., Vizcay-Barrena, G., Karp, N. A., Arends, M., Brenn, T., Spiegel, S., Adams, D. J., Watt, F. M. & van der Weyden, L. Jul 2016 The Journal of Pathology. 239, 3, p. 374–383

Squamoid Eccrine Ductal Carcinoma: A Clinicopathologic Study of 30 Cases van der Horst, M. P. J., Garcia-Herrera, A., Markiewicz, D., Martin, B., Calonje, E. & Brenn, T. 19 Jan 2016 The American journal of surgical pathology.

Cross-species models of human melanoma van der Weyden, L., Patton, E., Wood, G. A., Foote, A., Brenn, T., Arends, M. & Adams, D. J. 1 Jan 2016 The Journal of Pathology.

Malignant sweat gland tumors: an update Brenn, T. Jul 2015 Advances in Anatomic Pathology. 22, 4, p. 242-53 12 p.

Morphologically low-grade spiradenocarcinoma: a clinicopathologic study of 19 cases with emphasis on outcome and MYB expression van der Horst, M. P. J., Marusic, Z., Hornick, J. L., Luzar, B. & Brenn, T. Jul 2015 Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 28, 7, p. 944-53 10 p.

The spectrum of rare morphological variants of cutaneous epithelioid angiosarcoma Wood, A., Mentzel, T., van Gorp, J., Flucke, U., Huschka, U., Schneider, J., Bacchi, C. E., Calonje, E. & Brenn, T. May 2015 Histopathology. 66, 6, p. 856-63 8 p.

Angiosarkome der Haut: Neue Aspekte Brenn, T. Feb 2015 Der Pathologe. 36, 1, p. 70-7 8 p.

Histologisches Spektrum des malignen Melanoms Brenn, T. Feb 2015 Der Pathologe. 36, 1, p. 53-61 9 p.

A case of hypocomplementaemic urticarial vasculitis with cardiac valve involvement successfully treated with cyclophosphamide and high-dose glucocorticoids Hauser, B., McRorie, E., McKay, N., Brenn, T. & Amft, N. 5 Apr 2014 International journal of rheumatic diseases.

TERT promoter mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas Griewank, K. G., Schilling, B., Murali, R., Bielefeld, N., Schwamborn, M., Sucker, A., Zimmer, L., Hillen, U., Schaller, J., Brenn, T., Schadendorf, D. & Mentzel, T. Apr 2014 Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 27, 4, p. 502-8 7 p.

Pleomorphic dermal neoplasms: a review Brenn, T. Mar 2014 Advances in Anatomic Pathology. 21, 2, p. 108-30 23 p.

Vascuar Tumors Calonje, E. & Brenn, T. 2014 Lever’s Histopathology of the Skin. Elder, D. (ed.). 11th ed. Lippincott Williams & Wilkins

Atypical fibroxanthoma with pseudoangiomatous features: a histological and immunohistochemical mimic of cutaneous angiosarcoma Thum, C., Husain, E. A., Mulholland, K., Hornick, J. L. & Brenn, T. Dec 2013 Annals of Diagnostic Pathology. 17, 6, p. 502-7 6 p.

Primary cutaneous adenoid cystic carcinoma: a clinicopathologic and immunohistochemical study of 27 cases Ramakrishnan, R., Chaudhry, I. H., Ramdial, P., Lazar, A. J., McMenamin, M. E., Kazakov, D., Brenn, T. & Calonje, E. Oct 2013 The American journal of surgical pathology. 37, 10, p. 1603-11 9 p.

The impact of molecular morphology techniques on the expert diagnosis in melanocytic skin neoplasms Ferrara, G., Misciali, C., Brenn, T., Cerroni, L., Kazakov, D. W., Perasole, A., Russo, R., Ricci, R., Crisman, G., Fanti, P. A., Passarini, B. & Patrizi, A. Oct 2013 International Journal of Surgical Pathology. 21, 5, p. 483-92 10 p.

Merkel cell carcinoma with divergent differentiation: histopathological and immunohistochemical study of 15 cases with PCR analysis for Merkel cell polyomavirus Martin, B., Poblet, E., Rios, J. J., Kazakov, D., Kutzner, H., Brenn, T. & Calonje, E. Apr 2013 Histopathology. 62, 5, p. 711-22 12 p.

DNA repair and replication proteins as prognostic markers in melanoma Song, L., Robson, T., Doig, T., Brenn, T., Mathers, M., Brown, E. R., Doherty, V., Bartlett, J. M. S., Anderson, N. & Melton, D. W. Jan 2013 Histopathology. 62, 2, p. 343-350 8 p.

Atypical Fibroxanthoma Calonje, E., Komminoth, P. & Brenn, T. 2013 Pathology and Genetics of Tumours of Soft Tissue and Bone: World Health Organization Classification of Tumours, . Fletcher, C. D. M., Hogendoorn, P. C. W., Bridge, J. A. & Mertens , F. (eds.). 4th ed. WHO, Vol. 5

Cutaneous Mesenchymal Tumours Brenn, T. & Hornick, J. L. 2013 Practical Soft Tissue Pathology: A Diagnostic Approach. Hornick, J. L. (ed.).

Melanocytic Lesions of the Vulva and Vagina Brenn, T. & Calonje, E. 2013 Pathology of the Vulva and Vagina. Brown, L. (ed.). Springer London, p. 113-145 ( Essentials of Diagnostic Gynecological Pathology)

Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations Suchak, R., Wang, W-L., Prieto, V. G., Ivan, D., Lazar, A. J., Brenn, T. & Calonje, E. Dec 2012 The American journal of surgical pathology. 36, 12, p. 1883-91 9 p.

Pleomorphic dermal sarcoma: adverse histologic features predict aggressive behavior and allow distinction from atypical fibroxanthoma Miller, K., Goodlad, J. & Brenn, T. Sep 2012 The American journal of surgical pathology. 36, 9, p. 1317-26 10 p.

Spitz nevus with Homer-Wright rosette-like structures Miller, K., Hall, R. C. & Brenn, T. Jun 2012 The American Journal of dermatopathology. 34, 4, p. 457-9 3 p.

Pitfalls in the evaluation of melanocytic lesions Brenn, T. Apr 2012 Histopathology. 60, 5, p. 690-705 16 p.

Acantholytic disorders Brenn, T. 2012 McKee's Pathology of the Skin. Calonje, E., Brenn, T., Lazar, A. & McKee, P. (eds.). 4 ed. Elsevier Health Sciences

Association of galectin-3 expression with melanoma progression and prognosis Brown, E. R., Doig, T., Anderson, N., Brenn, T., Doherty, V., Xu, Y., Bartlett, J. M. S., Smyth, J. F. & Melton, D. W. 2012 European Journal of Cancer. 48, 6, p. 865-74 10 p.

Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors Xu, Y., Brenn, T., Brown, E. R. S., Doherty, V. & Melton, D. W. 2012 British Journal of Cancer. 106, 3, p. 553-61 9 p.

McKee's pathology of the skin: with clinical correlations Calonje, E., Brenn, T., Lazar, A. & McKee, P. H. 2012 4th ed. ed. Elsevier/Saunders. 1803 p.

Neoplasms of Subcutaneous Fat. Brenn, T. 2012 Fitzpatrick’s Dermatology in General Medicine. Goldsmith, L. A., Katz, S. I., Gilchrest, B. A., Paller, A., Leffell, D. J. & Wolff, K. (eds.). 8th Revised ed. McGraw Hill

Spongiotic, psoriasiform and pustular dermatoses. Brenn, T. 2012 McKee's Pathology of the Skin. Calonje, E., Brenn, T., Lazar, A. & McKee, P. (eds.). 4 ed. Elsevier Health Sciences

Superficial and deep perivascular inflammatory dermatoses Brenn, T. 2012 McKee's Pathology of the Skin. Calonje, E., Brenn, T., Lazar, A. & McKee, P. (eds.). 4 ed. Elsevier Health Sciences

Tumors of surface epithelium Brenn, T. 2012 McKee's Pathology of the Skin. Calonje, E., Brenn, T., Lazar, A. & McKee, P. (eds.). 4 ed. Elsevier Health Sciences

Tumors of the hair follicle. Brenn, T. 2012 McKee's Pathology of the Skin. Calonje, E., Brenn, T., Lazar, A. & McKee, P. (eds.). 4 ed. Elsevier Health Sciences

Tumors of the sweat glands Brenn, T. 2012 McKee's Pathology of the Skin. Calonje, E., Brenn, T., Lazar, A. & McKee, P. (eds.). 4 ed. Elsevier Health Sciences

Vascular diseases Brenn, T. 2012 McKee's Pathology of the Skin. Calonje, E., Brenn, T., Lazar, A. & McKee, P. (eds.). 4 ed. Elsevier Health Sciences

Aberrant Melan-A expression in atypical fibroxanthoma and undifferentiated pleomorphic sarcoma of the skin Thum, C., Hollowood, K., Birch, J., Goodlad, J. & Brenn, T. Dec 2011 Journal of Cutaneous Pathology. 38, 12, p. 954-60 7 p.

Atypical genital nevus Brenn, T. Mar 2011 Archives of Pathology and Laboratory Medicine. 135, 3, p. 317-20 4 p.

Melanotic schwannoma arising in association with nevus of Ota: 2 cases suggesting a shared mechanism Trufant, J. W., Brenn, T., Fletcher, C. D. M., Virata, A. R., Cook, D. L. & Bosenberg, M. W. Dec 2009 The American Journal of dermatopathology. 31, 8, p. 808-13 6 p.

Severely photosensitive psoriasis: a phenotypically defined patient subset Rutter, K. J., Watson, R. E. B., Cotterell, L. F., Brenn, T., Griffiths, C. E. M. & Rhodes, L. E. Dec 2009 Journal of Investigative Dermatology. 129, 12, p. 2861-7 7 p.

Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma Friedberg, J. W., Kelly, J. L., Neuberg, D., Peterson, D. R., Kutok, J. L., Salloum, R., Brenn, T., Fisher, D. C., Ronan, E., Dalton, V., Rich, L., Marquis, D., Sims, P., Rothberg, P. G., Liesveld, J., Fisher, R. I., Coffman, R., Mosmann, T. & Freedman, A. S. Aug 2009 British journal of haematology. 146, 3, p. 282-91 10 p.

Cutaneous and subcutaneous metastases of gastrointestinal stromal tumors: a series of 5 cases with molecular analysis Wang, W-L., Hornick, J. L., Mallipeddi, R., Zelger, B. G., Rother, J. D., Yang, D., Lev, D. C., Trent, J. C., Prieto, V. G., Brenn, T., Robson, A., Calonje, E. & Lazar, A. J. F. May 2009 The American Journal of dermatopathology. 31, 3, p. 297-300 4 p.

CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans Haining, W. N., Davies, J., Kanzler, H., Drury, L., Brenn, T., Evans, J., Angelosanto, J., Rivoli, S., Russell, K., George, S., Sims, P., Neuberg, D., Li, X., Kutok, J., Morgan, J., Wen, P., Demetri, G., Coffman, R. L. & Nadler, L. M. 1 Sep 2008 Clinical Cancer Research. 14, 17, p. 5626-34 9 p.

Melanoma in children and adolescents Brenn, T. & Mckee, P. H. 1 Jan 2008 Diagnostic Histopathology. 14, 1, p. 18-27

Atypical genital nevi. A clinicopathologic analysis of 56 cases Gleason, B. C., Hirsch, M. S., Nucci, M. R., Schmidt, B. A., Zembowicz, A., Mihm, M. C., McKee, P. H. & Brenn, T. Jan 2008 The American journal of surgical pathology. 32, 1, p. 51-7 7 p.

CD25 expression on cutaneous mast cells from adult patients presenting with urticaria pigmentosa is predictive of systemic mastocytosis Hollmann, T. J., Brenn, T. & Hornick, J. L. Jan 2008 The American journal of surgical pathology. 32, 1, p. 139-45 7 p.

Nodular presentation of secondary syphilis Tsai, K. Y., Brenn, T. & Werchniak, A. E. Aug 2007 Journal of the american academy of dermatology. 57, 2 Suppl, p. S57-8

Neoplasms of Subcutaneous Fat Brenn, T. 2007 Fitzpatrick’s Dermatology in General Medicine. Wolff, K., Goldsmith, L., Katz, S., Gilchrest, B., Paller, A. & Leffell, D. (eds.). McGraw Hill

Mohs micrographic surgery, sentinel lymph node mapping, and estrogen receptor analysis for the treatment of malignant nodular hidradenoma Tolland, J. P., Brenn, T., Guldbakke, K. K. & Schanbacher, C. F. Oct 2006 Dermatologic Surgery. 32, 10, p. 1294-301 8 p.

A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence Natarajan, E., Omobono, J. D., Guo, Z., Hopkinson, S., Lazar, A. J. F., Brenn, T., Jones, J. C. & Rheinwald, J. G. Jun 2006 American Journal Of Pathology. 168, 6, p. 1821-37 17 p.

Postradiation vascular proliferations: an increasing problem Brenn, T. & Fletcher, C. D. M. 1 Jan 2006 Histopathology. 48, 1, p. 106-114

Cutaneous Myoepithlioma Brenn, T. 2006 Cases in Dermatopathology. Common Problems in Diagnosis of Pigmented Lesions. Zembowicz, A., Flotte, T. J., Mihm, M. C., Murphy, G. F. & Tahan, S. R. (eds.). KBS Publishing

Radiation-associated cutaneous atypical vascular lesions and angiosarcoma: clinicopathologic analysis of 42 cases Brenn, T. & Fletcher, C. D. M. Aug 2005 The American journal of surgical pathology. 29, 8, p. 983-96 14 p.

Cutaneous Myoepithlioma Brenn, T. 2005 Cases in Dermatopathology. Adnexal Neoplasms. Zembowicz, A., Flotte, T. J., Mihm, M. C., Murphy, G. F. & Tahan, S. R. (eds.). KBS Publishing

Microcystic Adnexal Carcinoma Brenn, T. 2005 Cases in Dermatopathology. Adnexal Neoplasms. Zembowicz, A., Flotte, T. J., Mihm, M. C., Murphy, G. F. & Tahan, S. R. (eds.). KBS Publishing

Tumors of surface epithelium. Brenn, T. 2005 Pathology of the Skin. McKee, P. H., Calonje, E. & Granter, S. R. (eds.). 3 ed. Mosby Itd

Tumors of the hair follicle. Brenn, T. 2005 Pathology of the Skin. McKee, P. H., Calonje, E. & Granter, S. R. (eds.). 3 ed. Mosby Itd

Tumors of the sweat glands Brenn, T. 2005 Pathology of the Skin. McKee, P. H., Calonje, E. & Granter, S. R. (eds.). 3 ed. Mosby Itd

Vascular neoplasms Brenn, T., McKee, P. H. & Mihm, M. C. 2005 Cancer of the skin. Rigel, D. S., Friedman, R., Dzubow, L. M., Reintgen, D. S., Bystryn, J-C. & Marks, R. (eds.). W.B. Saunders

Cutaneous epithelioid angiomatous nodule: a distinct lesion in the morphologic spectrum of epithelioid vascular tumors Brenn, T. & Fletcher, C. D. M. Feb 2004 The American Journal of dermatopathology. 26, 1, p. 14-21 8 p.

Cutaneous rosai-dorfman disease is a distinct clinical entity Brenn, T., Calonje, E., Granter, S. R., Leonard, N., Grayson, W., Fletcher, C. D. M. & McKee, P. H. Oct 2002 The American Journal of dermatopathology. 24, 5, p. 385-91 7 p.

Premature termination mutations in FBN1: distinct effects on differential allelic expression and on protein and clinical phenotypes Schrijver, I., Liu, W., Odom, R., Brenn, T., Oefner, P., Furthmayr, H. & Francke, U. Aug 2002 American Journal of Human Genetics. 71, 2, p. 223-37 15 p.

Multi-exon deletions of the FBN1 gene in Marfan syndrome Liu, W., Schrijver, I., Brenn, T., Furthmayr, H. & Francke, U. 24 Oct 2001 BMC Medical Genetics. 2, p. 11

Cysteine substitutions in epidermal growth factor-like domains of fibrillin-1: distinct effects on biochemical and clinical phenotypes Schrijver, I., Liu, W., Brenn, T., Furthmayr, H. & Francke, U. Oct 1999 American Journal of Human Genetics. 65, 4, p. 1007-20 14 p.

Intracoronary Doppler flow velocity measurements in two patients with solitary coronary ostium: is there true obstruction? Schmidt, M. C., Klues, H. G., vom Dahl, J., Brenn, T., Hügel, W. & Hanrath, P. Oct 1996 Coronary artery disease. 7, 10, p. 761-5 5 p.

Mutant fibrillin-1 monomers lacking EGF-like domains disrupt microfibril assembly and cause severe marfan syndrome Liu, W., Qian, C., Comeau, K., Brenn, T., Furthmayr, H. & Francke, U. Oct 1996 Human Molecular Genetics. 5, 10, p. 1581-7 7 p.

Dermal fibroblast culture as a model system for studies of fibrillin assembly and pathogenetic mechanisms: defects in distinct groups of individuals with Marfan's syndrome Brenn, T., Aoyama, T., Francke, U. & Furthmayr, H. Sep 1996 Laboratory investigation. 75, 3, p. 389-402 14 p.

Expression of a mutant human fibrillin allele upon a normal human or murine genetic background recapitulates a Marfan cellular phenotype Eldadah, Z. A., Brenn, T., Furthmayr, H. & Dietz, H. C. Feb 1995 Journal of Clinical Investigation. 95, 2, p. 874-80 7 p.

Dual effect of nicotine on cardiac noradrenaline release during metabolic blockade Richardt, G., Brenn, T., Seyfarth, M., Haass, M., Schömig, E. & Schömig, A. 1 Nov 1994 Basic research in cardiology. 89, 6, p. 524-34 11 p.

Nicotine-induced release of noradrenaline and neuropeptide Y in guinea-pig heart: role of calcium channels and protein kinase C Haass, M., Richardt, G., Brenn, T., Schömig, E. & Schömig, A. Nov 1991 Naunyn-Schmiedebergs archives of pharmacology. 344, 5, p. 527-31 5 p.

Nicotine-induced release of noradrenaline and neuropeptide Y in the heart: dependence on calcium, potassium and pH Richardt, G., Haass, M., Brenn, T., Schömig, E. & Schömig, A. 1991 Effect of nicotine on biological systems. Adlkofer , F. & Thurau , K. (eds.). Birkhäuser, p. 197-203 (Advances in Pharmacological Sciences)